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Plumb’s
Veterinary Drug
Sixth Edition
Donald C. Plumb, Pharm.D.
distributed by
Blackwell Publishing
Handbook
COPyriGHt © 2008 by donald C. Plumb
All rights reserved. No part of this book may be reproduced or transmitted in any form or any means,
electronic or mechanical, including recording, photocopying, or by any information storage and retrieval system,
without the written permission of the copyright owner.
WORLDWIDE PRINT DISTRIBUTION BY:
Blackwell Publishing Professional
2121 south state Avenue
Ames, iowa 50014-8300
(800) 862-6657
www.blackwellpublishing.com/Vet/
PUBLISHED BY
PharmaVet Inc.
stockholm, Wisconsin
DESIGN AND TYPESETTING
Peregrine Graphics services
st. Paul, Minnesota
isbN: 978-0-8138-1097-3
Last digit is the print number 9 8 7 6 5 4 3 2 1
For Shirley,
Whose efforts, support, and love
make this reference a reality
* * *
Contributors to the Sixth Edition
C. A. tony bufington, dVM, Phd, dACVN
Professor of Veterinary Clinical sciences
the Ohio state university Veterinary Hospital
Columbus, OH
Dog and Cat Therapeutic Diets
Michelle duMond, rVt
Nutrition support specialist
the Ohio state university Veterinary Hospital
Columbus, OH
Dog and Cat Therapeutic Diets
Andrea G. Cannon, dVM, dACVd
Animal dermatology & Allergy
rocklin, CA; Modesto, CA; boise, id
Dermatological Agents, Topical
dinah Jordan, Pharmd, diCVP
Mississippi state university
Mississippi state, Ms
Insulin, Maropitant, & Mirtazapine Monographs
Gigi davidson, diCVP
North Carolina state university
raleigh, NC
Ophthalmology Products, Topical
Principles of Compounding Ophthalmic Products
sandra Koch, dVM, Ms, dACVd
College of Veterinary Medicine, university of
Minnesota
st. Paul, MN
Dermatological Agents, Topical
Camille deClementi, VMd, dAbt
AsPCA Animal Poison Control Center
urbana, iL
Overdose and Toxin Exposure Decontamination
Guidelines, ASPCA Animal Poison Control Center
Data for Drug Monographs
elaine Lust, Pharmd, diCVP
Creighton university
Omaha, Ne
Ceftiofur (Free Acid, Sodium and HCl), Danoloxacin,
Tulathromycin Monographs
to sign up for e-mail notiication of
updates and errata , or get information
on ordering information for additional
versions, visit Plumb’s Veterinary Drug
Handbook ’s web site at:
www.vetdruginfo.com
 
Preface to the Sixth Edition
in this edition, Plumb’s Veterinary Drug Handbook
continues to evolve with the addition of more
drugs, more types of drugs (topical dermatology
drugs), and a new look; however, the basic premise
remains to serve as a single volume reference to
assist veterinarians, other health professionals, and
animal caretakers in providing optimal drug therapy
for veterinary patients. the changes to this edition
include a new design and layout; the addition of
75 new drug monographs; updates to the older
monographs, with a listing for rapid-scanning for
potential drug interactions and overdose information
for 50 drugs from the AsPCA Animal Poison Control
Center; and new sections on topical dermatologic
agents and products, Principles of Compounding
Ophthalmic Products, and Overdose and toxin
exposure decontamination Guidelines in the
appendix.
donald C. Plumb
About the Author
donald C. Plumb, Pharm.d., was formerly director
of Pharmacy services and Hospital director at the
university of Minnesota’s Veterinary Medical Center.
Now retired from the university of Minnesota,
he focuses full-time on providing veterinary
drug information to veterinarians, other health
professionals, and animal caretakers.
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