Nanofabrication Towards Biomedical Applications - C. S. S. R. Kumar.pdf

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Nanofabrication Towards Biomedical Applications: Techniques, Tools, Applications, and Impact
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Nanofabrication Towards
Biomedical Applications
Techniques, Tools, Applications, and Impact
Edited by C. S. S. R. Kumar, J. Hormes, C. Leuschner
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Editors
& All books published by Wiley-VCH are carefully pro-
duced. Nevertheless, authors, editors, and publisher
do not warrant the information contained in these
books, including this book, to be free of errors.
Readers are advised to keep in mind that statements,
data, illustrations, procedural details or other items
may inadvertently be inaccurate.
Dr. Challa S. S. R. Kumar
Center for Advanced Microstructures and Devices
Louisiana State University
6980 Jefferson Highway
Baton Rouge, LA 70806
USA
ckumar1@lsu.edu
Library of Congress Card No.:
applied for
Prof. Dr. Josef Hormes
Center for Advanced Microstructures and Devices
Louisiana State University
6980 Jefferson Highway
Baton Rouge, LA 70806
USA
hormes@lsu.edu
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the
British Library.
Bibliographic information published by
Die Deutsche Bibliothek
Die Deutsche Bibliothek lists this publication in the
Deutsche Nationalbibliografie; detailed bibliographic
data is available in the Internet at
<http://dnb.ddb.de>.
Prof. Dr. Carola Leuschner
Reproductive Biotechnology Laboratory
Pennington Biomedical Research Centre
Louisiana State University
6400 Perkins Road
Baton Rouge, LA 70808
USA
leuschc@pbrc.edu
2005WILEY-VCH Verlag GmbH & Co. KGaA,
Weinheim
All rights reserved (including those of translation
into other languages). No part of this book may be
reproduced in any form – nor transmitted or trans-
lated into machine language without written permis-
sion from the publishers. Registered names, trade-
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specifically marked as such, are not to be considered
unprotected by law.
Printed in the Federal Republic of Germany.
Printed on acid-free paper.
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ISBN-13 978-3-527-31115-6
ISBN-10 3-527-31115-7
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V
Foreword
Nanobiotechnology: Hype, Hope and the Next Small Thing is the title of one of the
chapters in this book. This title suggests that the applications of nanotechnology in
biology and medicine are still in a somewhat uncertain future, but the contrary is
also true: there are already several products, such as zinc oxide nanoparticles in sun
cream or nano-silver as a coating material for home appliances to destroy bacteria
and prevent them from spreading, that are available on the market. Other, even
more exciting applications are in the testing phase, for example, using magnetic
nanoparticles for a targeted hyperthermia treatment of brain cancer. There are of
course also applications that might become reality in the far future – though there
are always surprises possible in nanotechnology, e.g., implantable pumps the size of
a molecule that deliver medicines with a precise dose when and where needed, or
the possibility to remove a damaged part of a cell and replacing it with a biological
machine. These applications are some of the goals stated in the National Institute of
Health roadmap for nanomedicine, which was established in spring 2003. This
initiative is again part of a larger US National Nanotechnology Initiative (NNI), for
which the President's budget will provide about $1 bn for 2005 for projects coordi-
nated by at least ten different federal agencies.
The book aptly named Nanofabrication Towards Biomedical Applications is timely
as the contributions are all written by experts in their field, summarizing the pres-
ent status of influence of nanotechnology in biology, biotechnology, medicine, edu-
cation, economy, society and industry. I am particularly impressed with the judi-
cious combination of chapters covering technical aspects of the various fields of
nanobiology and nanomedicine from synthesis and characterization of nanosystems
to practical applications, and the societal and educational impact of the emerging
new technologies. Thus, this book gives an excellent overview for non-specialists by
providing an up-to-date review of the existing literature in addition to providing new
insights for interested scientists, giving a jump-start into this emerging research
area. I hope this book will stimulate many scientists to start research in these excit-
ing and important directions. I am particularly pleased to recognize the efforts of
Nanofabrication Towards Biomedical Applications. C. S. S. R. Kumar, J. Hormes, C. Leuschner (Eds.)
Copyright 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
ISBN 3-527-31115-7
VI
Foreword
the Center for Advanced Microstructures and Devices (CAMD) and of the Penning-
ton Biomedical Research Center (PBRC) in taking a lead to spread the influence of
biomedical nanotechnology, and I am convinced that the book will be a valuable tool
in the hands of all those interested in discovering new paths and opportunities in
this fascinating new field.
William L. Jenkins
President, Louisiana State University
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