Science - July 2 2010.pdf

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CONTENTS
Volume 329 Issue 5987
EDITORIAL
13 Science Attachés in Embassies
Farouk El-Baz
FDA Regulations for Drug Development
R. E. Behrman and J. Woodcock
Response
A. D. Levinson
33 CORRECTIONS AND CLARIFICATIONS
NEWS OF THE WEEK
18 Confl icting Papers on Hold as XMRV
Frenzy Reaches New Heights
19 India Launches New Probe
of Cyanide Disaster
20 Evidence for Free-Flowing Supersolid
Slipping Away?
21 From Science ’s Online Daily News Site
21 From the Science Policy Blog
22 Hunting for Plumes, Learning to Live
in a Media Spotlight
23 How to Kill a Well So That It’s
Really Most Sincerely Dead
BOOKS ET AL.
34 Science Tourism:
Some Stops for Summer Trips
POLICY FORUM
38 Synthetic “Life,” Ethics, National Security,
and Public Discourse
M. K. Cho and D. A. Relman
>> Research Article p. 52; Science Podcast
page 24
PERSPECTIVES
40 Genes for High Altitudes
J. F. Storz
>> Reports pp. 72 and 75
41 Tropical Arthropod Species, More or Less?
R. M. May
42 Downsizing the Hydrated Electron’s Lair
K. D. Jordan and M. A. Johnson
>> Report p. 65
44 A Guardian of T Cell Fate
J. P. Di Santo
>> Reports pp. 85, 89, and 93
45 To Cool or Not to Cool
V. Bromm
>> Report p. 69
NEWS FOCUS
24 The Seductive Allure of
Behavioral Epigenetics
A Role for Epigenetics in Cognition
>> Science Podcast
28 In Archaeobotanist’s Hands,
Tiny Fossils Yield Big Answers
30 Righting a 65-Year-Old Wrong
LETTERS
32 Racial Differences in Breast Cancer Patterns
L. Shi
Cryptic Loss of India’s Native Forests
J.-P. Puyravaud et al.
Variability of Our Somatic (Epi)Genomes
V. Sgaramella
CONTENTS continued >>
page 34
COVER
Electron micrograph of Mycoplasma mycoides JCVI-syn1.0 cells
(magnifi cation ~25,000×). These cells were produced following
transplantation of a 1.08–megabase pair synthetic M. mycoides
genome into M. capricolum recipient cells. The cells are controlled by
the synthetic genome, exhibit the expected phenotypic properties, and
are capable of self-replication, thus providing proof of principle for the
production of cells from digitized sequence information. See page 52.
Photo: Thomas Deerinck and Mark Ellisman, National Center for
Microscopy and Imaging Research, University of California at San Diego
DEPARTMENTS
10 This Week in Science
14 Editors’ Choice
16 Science Staff
17 Random Samples
97 New Products
98 Science Careers
www.sciencemag.org SCIENCE VOL 329 2 JULY 2010
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