Science - December 2 2005.pdf

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2 December 2005

Vol. 310 No. 5753

Pages 1373–1568 $10

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© 2005 General Electric Company - All rights reserved.

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going to market as GE Healthcare.

GE18-05

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S PECIAL I SSUE

G ETTING A CROSS THE M EMBRANE

A variety of proteinaceous pores translocate ions, proteins, and DNA across cell mem-

branes. A special section in this issue looks at how they accomplish this essential task.

[Image: Chris Bickel]

Volume 310

2 December 2005

Number 5753

I NTRODUCTION

1451 Crossing the Bilayer

R EVIEWS

1452

1461

Principles of Selective Ion Transport in Channels and Pumps

E. Gouaux and R. MacKinnon

Protein Translocation Across Biological Membranes

W. Wickner and R. Schekman

For related online content in STKE

see page 1383 or go to

www.sciencemag.org/sciext/membranes/

1456

The Ins and Outs of DNA Transfer in Bacteria

I. Chen, P. J. Christie, D. Dubnau

D EPARTMENTS

N EWS F OCUS

1383

S CIENCE O NLINE

1410

E COLOGY

Winning the War Against Island Invaders

1385

T HIS W EEK IN S CIENCE

1389

E DITORIAL by Michael S. Turner

Bullish on Particles

1414

A COUSTIC E NGINEERING

String Theory Meets Practice as Violinmakers

Rethink Their Craft

1391

E DITORS ’C HOICE

1396

C ONTACT S CIENCE

1417

P ROFILE :F RANK W OLF

The Congressman With His Hand on Science’s

Purse Strings

1401

N ET W ATCH

1517

N EW P RODUCTS

1526

S CIENCE C AREERS

1418

P ALEONTOLOGY

Best Archaeopteryx Fossil So Far Ruffles

a Few Feathers

related Report page 1483

N EWS OF THE W EEK

1402

S TEM C ELL R ESEARCH

Korean Cloner Admits Lying

About Oocyte Donations

1421

R ANDOM S AMPLES

1410

L ETTERS

1403

G LOBAL C LIMATE C HANGE

The Atlantic Conveyor

May Have Slowed, But Don’t Panic Yet

1425

Issues in Bringing New Drugs to the Market

R. Ansbacher; A. J. Ammann; W. R. Tracey . Response

J. Avorn. Invariant Ratios Vs. Dimensionless Ratios

M. Mangel. Worldwide Decline of Sturgeons

D. E. Lorke and D. T. Yew

1405

C ANADA

Animal Rules Keep Grad Students

Out of the Lab

1429

Corrections and Clarifications

1405

S CIENCE S COPE

1406

N UCLEAR P OWER

Congress Tells DOE to Take Fresh Look at

Recycling Spent Reactor Fuel

B OOKS ET AL .

1432

N ATURAL H ISTORY

Return to Wild America

A Yearlong Search for the Continent’s Natural Soul

S. Weidensaul, reviewed by J. Greenberg

1407

S CIENTIFIC P UBLISHING

NIEHS Journal Is on the Block

1407

U.S. G RADUATE E DUCATION

Universities Must Pay to Play in

Ph.D. Program Rankings

1433

B EHAVIORAL E COLOGY

In the Company of Crows and Ravens

J. M. Marzluff and T. Angell, reviewed by J. Dally

1409

S PAC E S CIENCE

Fuel Shortage Imperils

Asteroid-Sampling Mission

E SSAY

1418 &

1483

1435

G LOBAL V OICES OF S CIENCE

Following the Light: Opening Doors

to Science in Tunisia

Z. B. Lakhdar

1409

E PIDEMIOLOGY

Talk on ‘Underground’ Bird Flu Deaths

Rattles Experts

Contents continued

1377

www.sciencemag.org

SCIENCE

VOL 310

2 DECEMBER 2005

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