Pathway Analysis for Drug Discovery - A. Yuryev (Wiley, 2008) WW.pdf

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PATHWAY ANALYSIS
FOR DRUG DISCOVERY
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Wiley Series on Technologies for the Pharmaceutical Industry
Sean Ekins, Series Editor
Editorial Advisory Board
Dr. Renee Arnold (ACT LLC, USA); Dr. David D. Christ (SNC Partners LLC,
USA); Dr. Michael J. Curtis (Rayne Institute, St Thomas’ Hospital, UK);
Dr. James H. Harwood (Pfi zer, USA); Dr. Dale Johnson (Emiliem, USA);
Dr. Mark Murcko, (Vertex, USA); Dr. Peter W. Swaan (University of Maryland,
USA); Dr. David Wild (Indiana University, USA); Prof. William Welsh (Robert
Wood Johnson Medical School University of Medicine & Dentistry of New Jersey,
USA); Prof. Tsuguchika Kaminuma (Tokyo Medical and Dental University,
Japan); Dr. Maggie A.Z. Hupcey (PA Consulting, USA); Dr. Ana Szarfman
(FDA, USA)
Computational Toxicology: Risk Assessment for Pharmaceutical and
Environmental Chemicals
Edited by Sean Ekins
Pharmaceutical Applications of Raman Spectroscopy
Edited by Slobodan Šaši´
Pathway Analysis for Drug Discovery: Computational Infrastructure and
Applications
Edited by Anton Yuryev
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PATHWAY ANALYSIS
FOR DRUG DISCOVERY
Computational Infrastructure
and Applications
Edited by
ANTON YURYEV
Ariadne Genomics, Inc.
Rockville, Maryland
A JOHN WILEY & SONS, INC., PUBLICATION
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Copyright © 2008 by John Wiley & Sons, Inc. All rights reserved.
Published by John Wiley & Sons, Inc., Hoboken, New Jersey.
Published simultaneously in Canada.
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Library of Congress Cataloging-in-Publication Data:
Pathway analysis for drug discovery : computational infrastructure and applications / [edited
by] Anton Yuryev.
p. ; cm. — (Wiley series on technologies for the pharmaceutical industry)
Includes bibliographical references and index.
ISBN 978-0-470-10705-8(cloth)
1. Drug development–Data processing. 2. DNA microarrays—Data processing.
3. Computationalbiology. I. Yuryev,Anton. II. Series.
[DNLM: 1. DrugDesign. 2. ComputationalBiology. 3. MicroarrayAnalysis—
methods. QV 744 P297 2008]
RM301.25.P3742008
615
2008015107
Printed in the United States of America.
10 9 8 7 6 5 4 3 2 1
.190285—dc22
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